Paul Buckmaster, DVM, PhD
Academic Appointments
- Associate Professor, Comparative Medicine
- Member, Bio-X
Contact Information
- Academic
Offices
Personal Information Email Tel (650) 498-4774
Professional Snapshot
Administrative Appointments
- Comparative Medicine Review Committee (RIRG-C) Study Section, NCRR, NIH (2008 - present)
- Research Council of the Professional Advisory Board, Epilepsy Foundation (2003 - present)
- Clinical Neuroplasticity and Neurotransmitter Study Section, NIH Center for Scientific Review (2004 - 2008)
Honors and Awards
- Career Award in the Biomedical Sciences, Burroughs Wellcome Fund (1996-2000)
Professional Education
| DVM: | University of California, Davis, Veterinary Medicine (1988) |
| PhD: | University of Washington, Physiology (1992) |
Postdoctoral Advisees
Graduate & Fellowship Program Affiliations
Scientific Focus
Research Interests
Temporal lobe epilepsy is common, frequently refractory to treatment, and devastating to those affected. Our long-term goal is to better understand the pathophysiological mechanisms of this disease so that rational and effective therapies can be developed. We use electrophysiological, molecular, and anatomical techniques to evaluate neuronal circuitry in normal and in epileptic brains.
Publications
- Dysfunction of the dentate basket cell circuit in a rat model of temporal lobe epilepsy. J Neurosci. 2009; (24): 7846-56
- Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy. J Neurosci. 2009; (25): 8259-69
- Surviving hilar somatostatin interneurons enlarge, sprout axons, and form new synapses with granule cells in a mouse model of temporal lobe epilepsy. J Neurosci. 2009; (45): 14247-56
- Synaptic input to dentate granule cell basal dendrites in a rat model of temporal lobe epilepsy. J Comp Neurol. 2008; (2): 190-202
- Changes in granule cell firing rates precede locally recorded spontaneous seizures by minutes in an animal model of temporal lobe epilepsy. J Neurophysiol. 2008; (5): 2431-42
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