Welcome to the Poston Lab

The Poston Lab seeks to understand the underlying brain circuitry associated with movement disorders, such as Parkinson’s disease, and specifically understand the changes in these circuits that lead to specific symptoms, including motor symptoms and cognitive/behavioral symptoms.  While current medical and surgical treatments can substantially improve many of the motor symptoms caused by Parkinson’s disease, none of the currently available treatments can cure the disease, alter the disease progression, or significantly treat many of the non-motor symptoms, such as memory problems. Our lab aims to bridge this treatment gap using functional and structural neuroimaging. In addition, we seek to develop novel neuroimaging biomarkers to improve diagnostic accuracy and monitor the efficacy of investigational treatments for Parkinson’s disease and other movement disorders.

Dr. Poston is also the Principle Investigator for clinical trials in movement disorders, such as gene-transfer therapy in Parkinson’s disease.